ISSN 1662-4009 (online)

ey0020.7-8 | Bone Health in Childhood Cancer Survivors | ESPEYB20

7.8. Risk and determinants of low and very low bone mineral density and fractures in a national cohort of Dutch adult childhood cancer survivors (DCCSS-LATER): a cross-sectional study

JE van Atteveld , DTC de Winter , VG Pluimakers , M Fiocco , RAJ Nievelstein , MGG Hobbelink , ACH de Vries , JJ Loonen , E van Dulmen-den Broeder , HJ van der Pal , SMF Pluijm , LCM Kremer , CM Ronckers , M van der Heiden-van der Loo , AB Versluijs , M Louwerens , D Bresters , HM van Santen , DS Olsson , I Hoefer , SAA van den Berg , J den Hartogh , WJE Tissing , SJCMM Neggers , MM van den Heuvel-Eibrink , Dutch LATER study group

Brief summary: This Dutch cross-sectional study aimed to assess risk factors for impaired bone mineral density (BMD) and fractures (particularly vertebral fractures) in adult survivors of childhood cancer. The relationships between low BMD (Z-score ≤–1), very low BMD (Z-score ≤–2), fractures, vertebral fractures, and demographic, treatment-related, endocrine, and lifestyle-related factors was analyzed by logistic regression.<p class=...

ey0020.7-15 | Long-Term Surveillance for Endocrine Complications in Childhood Cancer Survivors | ESPEYB20

7.15. Frailty and sarcopenia within the earliest national Dutch childhood cancer survivor cohort (DCCSS-LATER): a cross-sectional study

JE van Atteveld , DTC de Winter , VG Pluimakers , M Fiocco , RAJ Nievelstein , MGG Hobbelink , LCM Kremer , MA Grootenhuis , H Maurice-Stam , WJE Tissing , ACH de Vries , JJ Loonen , E van Dulmen-den Broeder , HJH van der Pal , SMF Pluijm , M van der Heiden-van der Loo , AB Versluijs , M Louwerens , D Bresters , HM van Santen , I Hoefer , SAA van den Berg , J den Hartogh , JHJ Hoeijmakers , SJCMM Neggers , MM van den Heuvel-Eibrink , Dutch LATER study group

Brief summary: This cross-sectional study explored the risk factors for pre-frailty, frailty, and sarcopenia in a cohort of Dutch childhood cancer survivors diagnosed between 1963 and 2001.Frailty was defined as the presence of at least two (pre-frailty) or three (frailty) of the following criteria: low appendicular lean mass (low percentage of lean tissue in the limbs assessed by dual-energy X-ray absorptiometry, DXA), low muscle strength (measured with...

ey0019.9-1 | Cancer treatment and growth hormone therapy: a consensus | ESPEYB19

9.1. Safety of growth hormone replacement in survivors of cancer and intracranial and pituitary tumours: a consensus statement

MCS Boguszewski , CL Boguszewski , W Chemaitilly , LE Cohen , J Gebauer , C Higham , AR Hoffman , M Polak , KCJ Yuen , N Alos , Z Antal , M Bidlingmaier , BMK Biller , G Brabant , CSY Choong , S Cianfarani , PE Clayton , R Coutant , AA Cardoso-Demartini , A Fernandez , A Grimberg , K Guðmundsson , J Guevara-Aguirre , KKY Ho , R Horikawa , AM Isidori , JOL Jorgensen , P Kamenicky , N Karavitaki , JJ Kopchick , M Lodish , X Luo , AI McCormack , L Meacham , S Melmed , Moab S Mostoufi , HL Muller , SJCMM Neggers , Oliveira MH Aguiar , K Ozono , PA Pennisi , V Popovic , S Radovick , L Savendahl , P Touraine , HM van Santen , G Johannsson

n.karavitaki@bham.ac.uk Eur J Endocrinol. 2022; 186: P35-P52. PMID: 35319491.Brief Summary: An international panel of experts produced this consensus statement after critical review of the existing evidence on the safety of GH replacement in cancer and intracranial tumour survivors and in patients with increased cancer risk. Current evidence does not support an association betwe...

ey0020.7-14 | Long-Term Surveillance for Endocrine Complications in Childhood Cancer Survivors | ESPEYB20

7.14. Hypothalamic-pituitary and other endocrine surveillance among childhood cancer survivors

L van Iersel , RL Mulder , C Denzer , LE Cohen , HA Spoudeas , LR Meacham , E Sugden , AYN Schouten-van Meeteren , EW Hoving , RJ Packer , GT Armstrong , S Mostoufi-Moab , AM Stades , D van Vuurden , GO Janssens , C Thomas-Teinturier , RD Murray , N Di Iorgi , SJCMM Neggers , J Thompson , AA Toogood , H Gleeson , C Follin , E Bardi , L Torno , B Patterson , V Morsellino , G Sommer , SC Clement , D Srivastava , CE Kiserud , A Fernandez , K Scheinemann , S Raman , KCJ Yuen , WH Wallace , LS Constine , R Skinner , MM Hudson , LCM Kremer , W Chemaitilly , HM van Santen

Brief summary: In this extensive and updated review, the International Late Effects of Childhood Cancer Guideline Harmonization Group (IGHG) report expert consensus-based guidelines that harmonize recommendations for surveillance of endocrine disorders in childhood cancer survivors.This interdisciplinary panel of 42 international experts formulated new surveillance recommendations for hypothalamic–pituitary (HP) dysfunction. Existing IGHG surveillan...